BDBM19026 1-[3-(aminomethyl)phenyl]-N-[4-(2-methanesulfonylphenyl)cyclohexyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::DPC 423 derivative, 6

SMILES CS(=O)(=O)c1ccccc1[C@@H]1CC[C@@H](CC1)NC(=O)c1cc(nn1-c1cccc(CN)c1)C(F)(F)F

InChI Key InChIKey=WWXSXVGKOQSOQE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19026   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM19026(1-[3-(aminomethyl)phenyl]-N-[4-(2-methanesulfonylp...)
Affinity DataKi:  2.00E+3nM ΔG°:  -7.69kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed