BDBM190238 US9174999, Table 1, Compound 6

SMILES OC1(O)CCN2C(=N)N[C@@H](COC(=O)N3CCCC3)[C@@H]3NC(=N)N[C@]123

InChI Key InChIKey=XKWZBFOVGJBRTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190238   

TargetSodium channel protein type 4 subunit alpha(Rat)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM190238(US9174999, Table 1, Compound 6)
Affinity DataIC50: 22.5nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium channel protein type 4 subunit alpha [I757A](Rat)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM190238(US9174999, Table 1, Compound 6)
Affinity DataIC50: 100nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium channel protein type 4 subunit alpha [M1240A](Rat)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM190238(US9174999, Table 1, Compound 6)
Affinity DataIC50: 500nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
In DepthDetails
US Patent