BDBM190229 US9175000, 14
SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1C(NC(C)C(N)=O)c1ccccc1)OC
InChI Key InChIKey=IYGNJGBBKBZIHX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 190229
Affinity DataEC50: 457nMpH: 7.4 T: 2°CAssay Description:[35S]GTPgammaS functional assays were conducted using freshly thawed pt-receptor membranes prepared in-house from a cell line expressing recombinant ...More data for this Ligand-Target Pair
Affinity DataEC50: 53nMpH: 7.4 T: 2°CAssay Description:[35S]GTPgammaS functional assays were conducted using freshly thawed pt-receptor membranes prepared in-house from a cell line expressing recombinant ...More data for this Ligand-Target Pair
Affinity DataEC50: 289nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells, CHO cells expressing the recombinant human kappa opioid receptor (kappa) were prepared by lysing cells in i...More data for this Ligand-Target Pair
Affinity DataEC50: 68.3nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant U-2 OS cells expressing the recombinant human kappa opioid receptor (kappa) were prepared by lysing cells in ice cold hypo...More data for this Ligand-Target Pair
Affinity DataKi: 40.1nMpH: 7.4Assay Description:Membranes from recombinant HEK-293 cells expressing the human κ opioid receptor (cloned in house) were prepared by lysing cells in ice cold hypo...More data for this Ligand-Target Pair
Affinity DataKi: 77.0nM ΔG°: -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membran...More data for this Ligand-Target Pair