BDBM190227 US9175000, 12
SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1C(NCC(O)=O)c1ccccc1)OC
InChI Key InChIKey=BPMRCXPJKCCXTE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 190227
Affinity DataEC50: 174nMpH: 7.4 T: 2°CAssay Description:[35S]GTPgammaS functional assays were conducted using freshly thawed pt-receptor membranes prepared in-house from a cell line expressing recombinant ...More data for this Ligand-Target Pair
Affinity DataEC50: 745nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells, CHO cells expressing the recombinant human kappa opioid receptor (kappa) were prepared by lysing cells in i...More data for this Ligand-Target Pair
Affinity DataKi: 52.2nMpH: 7.4Assay Description:Membranes from recombinant HEK-293 cells expressing the human κ opioid receptor (cloned in house) were prepared by lysing cells in ice cold hypo...More data for this Ligand-Target Pair