BDBM189989 US9175003, 148::US9175003, 179

SMILES CC[C@H](N1Cc2cc3O[C@H](COc3cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(cc1)-c1ccnc(C)c1C)C(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)c1ccccc1

InChI Key InChIKey=DEDPYBWOUXWMOX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189989   

TargetGlucagon-like peptide 1 receptor(Human)
Vtv Therapeutics

US Patent
LigandPNGBDBM189989(US9175003, 148 | US9175003, 179)
Affinity DataEC50:  13nMAssay Description:The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
Go to US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Vtv Therapeutics

US Patent
LigandPNGBDBM189989(US9175003, 148 | US9175003, 179)
Affinity DataEC50:  5nMAssay Description:The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
Go to US Patent