BDBM189327 Hexanoic acid (Compound A)::US9174940, Compound A

SMILES CC(=O)N1c2ccc(cc2C(C)(CC1(C)C)c1ccccc1)C(N)=O

InChI Key InChIKey=NWOPZZXYRMPIBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189327   

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189327(US9174940, Compound A | Hexanoic acid (Compound A))
Affinity DataIC50: 368nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189327(US9174940, Compound A | Hexanoic acid (Compound A))
Affinity DataIC50: 88nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent