BDBM18883 3,5-dibromo-4-[4-hydroxy-3,5-bis(propan-2-yl)phenoxy]benzoic acid::JMC496635 Compound 3::thyromimetic, 4

SMILES CC(C)c1cc(Oc2c(Br)cc(cc2Br)C(O)=O)cc(C(C)C)c1O

InChI Key InChIKey=PFUQJKKBXJZCRY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18883   

TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18883(JMC496635 Compound 3 | 3,5-dibromo-4-[4-hydroxy-3,...)
Affinity DataIC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18883(JMC496635 Compound 3 | 3,5-dibromo-4-[4-hydroxy-3,...)
Affinity DataIC50: 910nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18883(JMC496635 Compound 3 | 3,5-dibromo-4-[4-hydroxy-3,...)
Affinity DataIC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18883(JMC496635 Compound 3 | 3,5-dibromo-4-[4-hydroxy-3,...)
Affinity DataIC50: 910nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18883(JMC496635 Compound 3 | 3,5-dibromo-4-[4-hydroxy-3,...)
Affinity DataIC50: 912nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed