BDBM18863 (2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenoxy]-3,5-diiodophenyl}propanoic acid::diiodo isopropyl thyronine, 4

SMILES CC(C)c1cc(Oc2c(I)cc(C[C@@H](N)C(O)=O)cc2I)ccc1O

InChI Key InChIKey=RNNRJYLAQGIPJH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18863   

TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.140nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.110nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.141nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed