BDBM18810 2-amino-6-ethyl-5-[(4-methoxyphenyl)sulfanyl]-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one::Pyrrolo[2,3-d]pyrimidine analogue, 10

SMILES CCc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(OC)cc1

InChI Key InChIKey=OXLAVPAXRVTWSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18810   

TargetThymidylate synthase(Human)
Duquesne University

LigandPNGBDBM18810(2-amino-6-ethyl-5-[(4-methoxyphenyl)sulfanyl]-3H,4...)
Affinity DataIC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
Duquesne University

LigandPNGBDBM18810(2-amino-6-ethyl-5-[(4-methoxyphenyl)sulfanyl]-3H,4...)
Affinity DataIC50: 3.20E+4nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2007
Entry Details Article
PubMed