BDBM187387 US9169243, 35::US9908875, 35

SMILES COC1(C)CCN(CC1)c1cnc(cc1-n1cnc(c1)C1CC1)C(=O)Nc1csc(n1)-c1nncn1[C@@H](C)C(F)(F)F

InChI Key InChIKey=ZDAMMZVKCIUPQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 187387   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM187387(US9169243, 35 | US9908875, 35)
Affinity DataIC50: 2.20nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gilead Sciences

US Patent
LigandPNGBDBM187387(US9169243, 35 | US9908875, 35)
Affinity DataIC50: 2.20nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair
In DepthDetails
US Patent