BDBM187371 US9169243, 19::US9908875, 19

SMILES O=C(Nc1csc(n1)-c1nncn1C1CC1)c1cc(c(cn1)N1CCN(CC1)C1CC1)-n1cnc(c1)C1CC1

InChI Key InChIKey=GGXVCKICZMCCLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 187371   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM187371(US9169243, 19 | US9908875, 19)
Affinity DataIC50: 2.80nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gilead Sciences

US Patent
LigandPNGBDBM187371(US9169243, 19 | US9908875, 19)
Affinity DataIC50: 2.80nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
Go to US Patent