BDBM187258 US9169234, 23

SMILES Cc1c(c2cc(ccc2[nH]1)O)CCNC(=O)COC

InChI Key InChIKey=YBXBWBBVLXZQBJ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 187258   

TargetSepiapterin reductase(Human)
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50: 11nMpH: 6.5 T: 2°CAssay Description:To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetSepiapterin reductase(Human)
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50: 12nMpH: 6.5 T: 2°CAssay Description:To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetSepiapterin reductase(Human)
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50: 310nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)