BDBM185963 US9163008, 52::US9656968, Compound 52

SMILES CC1(C)OCC(CN(c2cc(nc(n2)-c2ccc(Oc3ccc(F)cc3)cc2)C(N)=O)S(C)(=O)=O)O1

InChI Key InChIKey=FSOVHPVLGSQHOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185963   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM185963(US9163008, 52 | US9656968, Compound 52)
Affinity DataIC50: 88nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
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TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM185963(US9163008, 52 | US9656968, Compound 52)
Affinity DataIC50: 88nMAssay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
Go to US Patent