BDBM185923 US9163008, 12::US9656968, Compound 12

SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(c(c2)C#N)C(F)(F)F)cc1)C(N)=O)C(N)=O

InChI Key InChIKey=PBGFEXXPIPCABZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185923   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM185923(US9163008, 12 | US9656968, Compound 12)
Affinity DataIC50: 400nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
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TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM185923(US9163008, 12 | US9656968, Compound 12)
Affinity DataIC50: 400nMAssay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
Go to US Patent