BDBM182734 US9145408, 369
SMILES N[C@]12CCC[C@H](C[C@@H](C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CC2CCCC(C2)C1
InChI Key InChIKey=HOWIQHYXNHBQBA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 182734
Affinity DataEC50: 545nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataKi: 178nM ΔG°: -8.55kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataKi: 4.03E+3nM ΔG°: -7.35kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataKi: 5.35E+3nM ΔG°: -6.68kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nM ΔG°: >-6.41kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair