BDBM181160 US9139529, 3::US9783501, Compound 3

SMILES NS(=O)(=O)c1cccc(NC(=O)c2nc3ccccc3nc2Oc2ccc(OC(F)(F)F)cc2)c1

InChI Key InChIKey=OCTAMESHNWXGHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181160   

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181160(US9139529, 3 | US9783501, Compound 3)
Affinity DataIC50: 14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181160(US9139529, 3 | US9783501, Compound 3)
Affinity DataIC50: 14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails
US Patent