BDBM179738 US9127005, NFW

SMILES Fc1ccc(cc1)[C@H]1CNC(=O)C11CCN(CCNC(=O)c2ccc(F)cc2)CC1

InChI Key InChIKey=BPCQYJWHRHUHQC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179738   

TargetPhospholipase D1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM179738(US9127005, NFW)
Affinity DataIC50: 1.10E+4nMAssay Description:In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPhospholipase D1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM179738(US9127005, NFW)
Affinity DataIC50: 480nMAssay Description:In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPhospholipase D1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM179738(US9127005, NFW)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM179738(US9127005, NFW)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed