BDBM178094 {[7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}(methyl)amine (Compound 6)

SMILES CNCC1Cc2cc(F)cc(c2O1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=KYLAEKGVXSXQOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 178094   

TargetAquaporin-1(Human)
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM178094({[7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)
Affinity DataIC50: 2.94E+4nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetAquaporin-1(Human)
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM178094({[7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of human AQP1 water channel expressed in CHO cells incubated for 10 mins by FLIPR Tetra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed