BDBM177866 US9120791, Example 91::US9603854, 91

SMILES Cc1ccc(cc1F)N(C(=O)c1cc(-c2cc(F)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc(O)cc1

InChI Key InChIKey=HNTZUGXIJANEQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177866   

TargetApoptosis regulator Bcl-2(Mouse)
Les Laboratoires Servier

US Patent
LigandPNGBDBM177866(US9120791, Example 91 | US9603854, 91)
Affinity DataIC50: 8nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApoptosis regulator Bcl-2(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM177866(US9120791, Example 91 | US9603854, 91)
Affinity DataIC50: 8nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
In DepthDetails
US Patent