BDBM17660 (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid::2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid::CHEMBL279956::Quisqualate::Quisqualate, L::quisqualic acid

SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O

InChI Key InChIKey=ASNFTDCKZKHJSW-UHFFFAOYSA-N

Data  38 KI  2 IC50  21 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 61 hits for monomerid = 17660   

TargetMetabotropic glutamate receptor 5(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  150nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for half maximal stimulation of PI hydrolysis (mGluR1a)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  750nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1c in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  300nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataIC50: 9.50E+3nMpH: 7.4 T: 2°CAssay Description:The inhibition concentration values of GCPII were determined using the radioenzymatic assay with [3H] NAAG (radiolabeled on the terminal glutamate). ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  200nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5b in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  200nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1a in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >5.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystine/glutamate transporter(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of amino acid transport system xc-More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >5.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 8(Mouse)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  1.64E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  4.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR3 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >5.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  2.50E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  300nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  630nMAssay Description:Agonist activity at mGlu5 receptor (unknown origin) expressed in CHO cells assessed as increase in Gq-mediated PI hydrolysis after 45 mins by yttrium...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, kainate 4(Human)
Allelix Biopharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  6.43nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  10nMAssay Description:Inhibition of binding to rat mGluR1a (metabotropic glutamate receptor) expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor(Rabbit)
University of Bristol

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  16.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate metabotropic receptor 5(Guinea pig)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  22nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  29nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate metabotropic receptor 5(Guinea pig)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  47nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  55nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  171nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  178nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  200nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  250nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
University of Minnesota

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  260nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  260nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  420nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  1.10E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  1.67E+3nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  6.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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