BDBM17592 CHEMBL169958::N'-[(2S,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxypentanoyl]-3-chlorobenzohydrazide::bestatin-type inhibitor, 7

SMILES CCSCC[C@@H](N)[C@H](O)C(=O)NNC(=O)c1cccc(Cl)c1

InChI Key InChIKey=IEOPIQXXSVCWPZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17592   

TargetMethionine aminopeptidase 2(Human)
Abbott Laboratories

LigandPNGBDBM17592(N'-[(2S,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxypen...)
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details
PubMed
TargetMethionine aminopeptidase 1(Human)
Abbott Laboratories

LigandPNGBDBM17592(N'-[(2S,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxypen...)
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details
PubMed
TargetMethionine aminopeptidase 2(Human)
Abbott Laboratories

LigandPNGBDBM17592(N'-[(2S,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxypen...)
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against human methionine aminopeptidase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Abbott Laboratories

LigandPNGBDBM17592(N'-[(2S,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxypen...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed