BDBM175286 3-(4-Aminosulfonylphenylamino)-2-(4-fluorophenyl)-5-methyl-4-thiazolidinone (8d)

SMILES CC1SC(N(Nc2ccc(cc2)S(N)(=O)=O)C1=O)c1ccc(F)cc1

InChI Key InChIKey=WHTODUGHHJDLQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175286   

TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

LigandPNGBDBM175286(3-(4-Aminosulfonylphenylamino)-2-(4-fluorophenyl)-...)
Affinity DataIC50: 1.08E+4nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandPNGBDBM175286(3-(4-Aminosulfonylphenylamino)-2-(4-fluorophenyl)-...)
Affinity DataIC50: 1.90E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed