BDBM175281 2-(4-(4-Isobutylphenyl)thiazol-2-ylimino)thiazolidin-4-one (4b)

SMILES CC(C)Cc1ccc(cc1)-c1csc(N=C2NC(=O)CS2)n1

InChI Key InChIKey=JMHARWVPXPHBEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175281   

TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

LigandPNGBDBM175281(2-(4-(4-Isobutylphenyl)thiazol-2-ylimino)thiazolid...)
Affinity DataIC50: 1.76E+4nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandPNGBDBM175281(2-(4-(4-Isobutylphenyl)thiazol-2-ylimino)thiazolid...)
Affinity DataIC50: 6.10E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed