BDBM175206 US9115126, Example 4b

SMILES Cc1cccc(n1)N1CCC(CCOc2ccc(cc2C(F)(F)F)-c2cc3n(C)nnc3c(n2)C#N)CC1

InChI Key InChIKey=OKJYCTOXUDPOFF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175206   

TargetCathepsin S(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM175206(US9115126, Example 4b)
Affinity DataIC50: 9nMAssay Description:The inhibitory activity of the compounds of the invention was demonstrated in vitro by measuring the inhibition of recombinant human Cathepsin S as f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent