BDBM175204 US9115126, Example 35

SMILES CN(C)CCCOc1ccc(cc1C(F)(F)F)-c1cc2n(C)nnc2c(n1)C#N

InChI Key InChIKey=QHHYEOKIFJXFKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175204   

TargetCathepsin S(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM175204(US9115126, Example 35)
Affinity DataIC50: 3.30nMAssay Description:The inhibitory activity of the compounds of the invention was demonstrated in vitro by measuring the inhibition of recombinant human Cathepsin S as f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent