BDBM174960 US9096593, P-2154

SMILES COc1ccc(CNc2ncc(Cc3c[nH]c4ncc(Cl)cc34)s2)cn1

InChI Key InChIKey=UYPBOKNKYJTLNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 174960   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Plexxikon

US Patent
LigandPNGBDBM174960(US9096593, P-2154)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of Fms kinase activity, where inhibition of phosphorylati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
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TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM174960(US9096593, P-2154)
Affinity DataIC50: 100nMpH: 7.5Assay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of c-Kit kinase activity, where inhibition of phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent