BDBM173621 US9096627, CY190602

SMILES Cn1c(CCCC(O)=O)nc2cc(ccc12)N(CCCl)CCCl

InChI Key InChIKey=YTKUWDBFDASYHO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 173621   

TargetHistone deacetylase 1(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 17nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 9nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 25nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 6nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 107nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 72nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed