BDBM173539 (E)-N'-(3-hydroxy-4-methoxybenzylidene)-1H-indole-2-carbohydrazide (11)

SMILES COc1ccc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc1O

InChI Key InChIKey=LWLUJJYQXFNMPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173539   

TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM173539((E)-N'-(3-hydroxy-4-methoxybenzylidene)-1H-ind...)
Affinity DataIC50: 1.91E+5nMAssay Description:The 135 µL of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 µL of test sample with 70% DMSO added into the wells. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProbable maltase-glucoamylase 2(Human)
Babasaheb Bhimrao Ambedkar University (A Central University)

Curated by ChEMBL
LigandPNGBDBM173539((E)-N'-(3-hydroxy-4-methoxybenzylidene)-1H-ind...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using pNPG as substrate preincubated for 10 mins followed by substrate addition measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed