BDBM173506 1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-(4-trifluoromethyl-phenyl)-4,5-di-hydro-1H-pyrazole (14a)

SMILES CS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(cc1)C(F)(F)F)c1ccc(O)cc1

InChI Key InChIKey=OHTTWGMJYXCLSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173506   

TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

LigandPNGBDBM173506(1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-...)
Affinity DataIC50: 1.73E+4nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandPNGBDBM173506(1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-...)
Affinity DataIC50: 6.70E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed