BDBM172673 US9090628, 333::US9090628, 339::US9090628, 341

SMILES CCN(CC)C1CCOC(C1)c1c(cnn1C)-c1ccc2-c3nc(cn3CCOc2c1)-c1nc(C)nn1C(C)C

InChI Key InChIKey=JUCFCEMDRWPMSZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 172673   

LigandPNGBDBM172673(US9090628, 341 | US9090628, 339 | US9090628, 333)
Affinity DataIC50: 2.37nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM172673(US9090628, 341 | US9090628, 339 | US9090628, 333)
Affinity DataIC50: 1.07nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM172673(US9090628, 341 | US9090628, 339 | US9090628, 333)
Affinity DataIC50: 0.771nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent