BDBM172588 US9090628, 248::US9090628, 309::US9090628, 310

SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)-c1cnn(C)c1C1CCCN(C1)C(C)(C)CO

InChI Key InChIKey=MANLYGWZZVOIHV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 172588   

LigandPNGBDBM172588(US9090628, 310 | US9090628, 309 | US9090628, 248)
Affinity DataIC50: 0.445nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM172588(US9090628, 310 | US9090628, 309 | US9090628, 248)
Affinity DataIC50: 0.485nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM172588(US9090628, 310 | US9090628, 309 | US9090628, 248)
Affinity DataIC50: 0.262nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent