BDBM17247 3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-5-propyl-4H,5H,6H-thieno[2,3-c]pyrrole-2-carboxamide::thiophene-containing non-amidine inhibitor, 49

SMILES CCCN1Cc2sc(C(=O)Nc3ccc(Cl)cc3C(=O)Nc3ccc(Cl)cc3)c(Cl)c2C1

InChI Key InChIKey=FWEQTRFUWAMPTQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17247   

TargetCoagulation factor X(Human)
Berlex

LigandPNGBDBM17247(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi:  2.20nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex

LigandPNGBDBM17247(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi:  3.20E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed