BDBM172459 US9090628, 101::US9090628, 102::US9090628, 103::US9090628, 104

SMILES CN1CCCCC1C1CCCN1c1cc2OCCn3cc(nc3-c2cn1)-c1nc(C)nn1CC(F)(F)F

InChI Key InChIKey=BTRBVLVZBYMHDD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 172459   

LigandPNGBDBM172459(US9090628, 102 | US9090628, 104 | US9090628, 103 |...)
Affinity DataIC50: 0.102nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM172459(US9090628, 102 | US9090628, 104 | US9090628, 103 |...)
Affinity DataIC50: 0.107nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM172459(US9090628, 102 | US9090628, 104 | US9090628, 103 |...)
Affinity DataIC50: 0.106nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM172459(US9090628, 102 | US9090628, 104 | US9090628, 103 |...)
Affinity DataIC50: 0.587nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails
US Patent