BDBM17232 N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-3-[(dimethylamino)methyl]-1-benzothiophene-2-carboxamide::benzothiophene compound, 11

SMILES CN(C)Cc1c(sc2ccccc12)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=GUWHVNCCIYIYIP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17232   

TargetCoagulation factor X(Human)
Berlex

LigandPNGBDBM17232(N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-3...)
Affinity DataKi:  9nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex

LigandPNGBDBM17232(N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-3...)
Affinity DataKi:  1.20E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Berlex

LigandPNGBDBM17232(N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-3...)
Affinity DataKi: >5.00E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed