BDBM171372 US9085571, Table 1, Compound 20

SMILES Cc1cc(cc(c1)C(=O)N(C)Cc2c(oc(n2)C)C)C(=O)N[C@@H](Cc3ccccc3)[C@@H](CN(CC(C)C)S(=O)(=O)c4ccc(cc4)OC)O

InChI Key InChIKey=VYTQZAGDUBREEP-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 171372   

TargetProtease(Human immunodeficiency virus type 1)
Purdue Research Foundation

US Patent
LigandPNGBDBM171372(US9085571, Table 1, Compound 20)
Affinity DataKi:  0.200nM IC50: 30nMAssay Description:Without being bound by theory, it is suggested that the compounds described herein may exert their utility by the inhibition of proteases encoded by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
Go to US Patent

TargetProtease(Human immunodeficiency virus type 1)
Purdue Research Foundation

US Patent
LigandPNGBDBM171372(US9085571, Table 1, Compound 20)
Affinity DataKi:  0.210nMAssay Description:Inhibition of HIV-1 protease by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed