BDBM171323 US9085555, 753

SMILES NC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc12

InChI Key InChIKey=UFIYIMOWCVCOJB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 171323   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM171323(US9085555, 753)
Affinity DataIC50: 66nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM171323(US9085555, 753)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM171323(US9085555, 753)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed