BDBM170763 US9085555, 191

SMILES NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2)c2ccccc12

InChI Key InChIKey=PFNAXJGGZUYQGP-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 170763   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM170763(US9085555, 191)
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetCytochrome P450 2C9(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM170763(US9085555, 191)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin) using diclofenac as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM170763(US9085555, 191)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)