BDBM168624 US9079852, Table F, Compound 9

SMILES O[C@H](COc1ccc2NC(=O)Cc2c1)CN1CCN(CC1)c1ccc(Cl)cc1

InChI Key InChIKey=RUXMKHKIUOUGFV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 168624   

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168624(US9079852, Table F, Compound 9)
Affinity DataIC50: 100nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM168624(US9079852, Table F, Compound 9)
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM168624(US9079852, Table F, Compound 9)
Affinity DataIC50: 370nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168624(US9079852, Table F, Compound 9)
Affinity DataKi:  1.00E+4nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent