BDBM168435 US9675571, 129

SMILES CC(C)CN(C1CCCCC1)c1ccc(cc1NC(=O)Nc1cc(C)no1)[C@H]1C[C@H]1C(O)=O

InChI Key InChIKey=JFOVWQVFKHJGRN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 168435   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM168435(US9675571, 129)
Affinity DataEC50:  0.5nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM168435(US9675571, 129)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM168435(US9675571, 129)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells incubated for 20 mins by Ehrlich's reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed