BDBM16809 (2S)-2-[(2,6-dichlorophenyl)formamido]-3-{4-[2-(2-hydroxyethyl)-5-methoxy-3-oxo-2,3-dihydropyridazin-4-yl]phenyl}propanoic acid::pyridazinone-based antagonist, 11

SMILES COc1cnn(CCO)c(=O)c1-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(O)=O)cc1

InChI Key InChIKey=BVCWBPBHALGRTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16809   

TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16809((2S)-2-[(2,6-dichlorophenyl)formamido]-3-{4-[2-(2-...)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16809((2S)-2-[(2,6-dichlorophenyl)formamido]-3-{4-[2-(2-...)
Affinity DataIC50: 2nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed