BDBM167931 1,5-dimethyl-2-phenyl-4-(2-(phenylsulfonyl)acetyl)-1H-pyrazol-3(2H)-one (1)

SMILES Cc1c(C(=O)CS(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=XAUUYFMHCZGINF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 167931   

TargetDipeptidyl peptidase 4 [K6R,T557I](Human)
Cairo University

LigandPNGBDBM167931(1,5-dimethyl-2-phenyl-4-(2-(phenylsulfonyl)acetyl)...)
Affinity DataIC50: 1.01E+4nMT: 2°CAssay Description:A 200-µL reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Northwest University

Curated by ChEMBL
LigandPNGBDBM167931(1,5-dimethyl-2-phenyl-4-(2-(phenylsulfonyl)acetyl)...)
Affinity DataIC50: 6.37E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
Pcte Group of Institutes

Curated by ChEMBL
LigandPNGBDBM167931(1,5-dimethyl-2-phenyl-4-(2-(phenylsulfonyl)acetyl)...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of DPP-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed