BDBM167515 US9073917, 12- comparative

SMILES CCOC(=O)c1[nH]cc2[C@@H](c3ccc(Sc4nc5ccccc5[nH]4)o3)C3=C(CCCC3=O)Nc12

InChI Key InChIKey=QNOOVTZVMOOSAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 167515   

TargetAurora kinase B/Inner centromere protein(Human)
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAurora kinase A(Human)
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50: 68nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Ev que, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails
US Patent