BDBM167275 US9073881, 24

SMILES OC(=O)c1cc(ccc1-c1ccccc1[N+]([O-])=O)-c1nc(cs1)-c1cccc(F)c1

InChI Key InChIKey=IRNHWJZMWSALDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167275   

TargetEukaryotic translation initiation factor 4E(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM167275(US9073881, 24)
Affinity DataIC50: 2.60E+3nMpH: 7.0Assay Description:Human eIF4E (aa 28-217) with a C-terminal His tag (HH-eIF4E) was expressed in E. coli in inclusion bodies. The protein was solubilized with 8 M urea ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent