BDBM165921 US10214524, Example 3::US9067931, 3

SMILES OCc1ccc(cc1)-c1ccc2cc(oc2c1)C(=O)N[C@H]1CN2CCC1CC2

InChI Key InChIKey=XVTVUSYKOFWVTB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165921   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165921(US9067931, 3 | US10214524, Example 3)
Affinity DataKi:  60nM ΔG°:  -9.15kcal/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165921(US9067931, 3 | US10214524, Example 3)
Affinity DataKi:  60nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent