BDBM165916 US9067924, 10

SMILES CC1(C)C(N)=N[C@@](C)(CCS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F

InChI Key InChIKey=DCVHGDNPQBRTDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165916   

TargetBeta-secretase 2(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM165916(US9067924, 10)
Affinity DataIC50: 181nMAssay Description:An ELISA assay (using a pair of mouse anti-human-TMEM27 antibodies, raised against the extracellular domain of TMEM27) is used for detection of TMEM2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent

TargetBeta-secretase 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM165916(US9067924, 10)
Affinity DataIC50: 62nMAssay Description:An ELISA assay (using a pair of mouse anti-human-TMEM27 antibodies, raised against the extracellular domain of TMEM27) is used for detection of TMEM2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent