BDBM165194 4‐Chloro‐7‐nitro‐3‐[(5‐phenylpentyl)oxy]isochromen‐1‐one (21)

SMILES [O-][N+](=O)c1ccc2c(Cl)c(OCCCCCc3ccccc3)oc(=O)c2c1

InChI Key InChIKey=VKSNRCDTOIDGQI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 165194   

TargetRhomboid domain-containing protein(Aquifex aeolicus (strain VF5))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRhomboid domain-containing protein(Pyrococcus horikoshii (strain ATCC 700860 / DSM 12...)
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRhomboid domain-containing protein(Thermotoga maritima (strain ATCC 43589 / MSB8 / DS...)
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlpG protein(Vibrio cholerae)
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 7.60E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRhomboid protease AarA(Providencia stuartii)
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRhomboid protease GlpG(Haemophilus influenzae (g-Proteobacteria))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 4.60E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRhomboid protease GluP [F193S,L370F,L379S,R499W](Bacillus subtilis (strain 168))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRhomboid-related protein 1(Mouse)
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 3.90E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRhomboid-related protein 3(Mouse)
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50: 2.40E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed