BDBM163640 5,11Dimethyl3(piperazin1yl)8thia4,6diazatricyclo[7.4.0.0 ,⁷]trideca1(9),2(7),3,5tetraene (Inh 5)::US9334288, 5
SMILES CC1CCc2c(C1)sc1nc(C)nc(N3CCNCC3)c21
InChI Key InChIKey=SVALUENWPLKUMZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 163640
Affinity DataIC50: 231nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Affinity DataEC50: 92.4nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Affinity DataIC50: 213nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Affinity DataEC50: 99.9nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
TargetBeta-galactosidase [V151I,I185V](Clostridium perfringens)
University of North Carolina At Chapel Hill
University of North Carolina At Chapel Hill
Affinity DataKi: 540nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
TargetBeta-galactosidase(Streptococcus agalactiae (Firmicutes))
University of North Carolina At Chapel Hill
University of North Carolina At Chapel Hill
Affinity DataKi: 810nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair