BDBM163022 US9056865, A-149

SMILES Cc1cc(F)cnc1-c1cc(ncc1Cl)N1CCC(CC1)NS(=O)(=O)CCO

InChI Key InChIKey=JKCRRWRQNIBLLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163022   

TargetSmoothened homolog(Human)
Pfizer

US Patent
LigandPNGBDBM163022(US9056865, A-149)
Affinity DataIC50: 20.7nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails
US Patent