BDBM162855 US9056843, 146

SMILES CCCN(CC)C[C@@H](C)NC(=O)c1ccc(cc1F)-c1noc(n1)C(F)(F)F

InChI Key InChIKey=HPKMFYOAMOHAPX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 162855   

TargetHistone deacetylase 1(Human)
Novartis

US Patent
LigandPNGBDBM162855(US9056843, 146)
Affinity DataIC50: 5.10E+3nMpH: 8.0 T: 2°CAssay Description:A similar assay procedure as described in Test 2 was used for HDAC1. Human recombinant full length HDAC1 expressed in a baculovirus expression system...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4(Human)
Novartis

US Patent
LigandPNGBDBM162855(US9056843, 146)
Affinity DataIC50: 1.60nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM162855(US9056843, 146)
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:A similar assay procedure as described in Test 2 was used for HDAC6. Human recombinant full length HDAC6 expressed in a baculovirus expression system...More data for this Ligand-Target Pair
In DepthDetails
US Patent