BDBM162576 US9687479, 56 2-[3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1-(2,2-dimethylpropanoyl)-1H-pyrazol-3-yl)-2-oxo-1,2-dihydropyridin-1-yl]acetonitrile

SMILES CC(C)(C)C(=O)n1nc(cc1NCc1sc(Cl)cc1Cl)-c1cccn(CC#N)c1=O

InChI Key InChIKey=NFBSJEHGEMWLEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162576   

TargetProthrombin(Human)
Verseon

US Patent
LigandPNGBDBM162576(US9687479, 56 2-[3-(5-[(5-chlorothiophen-2-yl)meth...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Human thrombin was obtained from Haematologic Technologies Inc. The chromogenic substrate S-2238 was obtained from DiaPharma. Thrombin was assayed in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
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